Genome Editing - Research and Reproduction

AuthorMaureen McTeer
[  ]
– chapter fourteen –
Genome Editing —
Research and Reproduction
Science in the eld of human genome editing has moved forward signi-
cantly during the past decade, which has raised serious and controversial
questions about its purpose and limits. While Canadians might approve
of research that leads to clinical treatments and even cures for serious and
fatal genetic conditions, there is no consensus on its use for enhancing the
human body. Nor has there been any signicant public or Parliamentary
discussion and debate about heritable human genome editing, which
would allow for changes in the germline of one person to be passed on
to their future progeny. One scholar has described it this way:
Heritable genome editing involves the transfer of genetically modied
embryos to a uterus to initiate a pregnancy that would result in the
birth of a child with a modied genome. Like heritable genome editing,
germline genome editing also involves making genetic modications to
gamete precursor cells, eggs, sperm, or early-stage embryos in the labora-
tory; unlike heritable human genome editing, any resulting genetically
modied embryos are not used for reproduction.
It is this reproductive step following the genetic editing of the human
genome that has been the most serious cause of controversy.

To continue reading

Request your trial

VLEX uses login cookies to provide you with a better browsing experience. If you click on 'Accept' or continue browsing this site we consider that you accept our cookie policy. ACCEPT